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Metformin ER
Description
Details
Benefits
- • Supports healthy aging and metabolic function
- • May promote steady energy throughout the day
- • May assist with weight management goals
- • Easy-to-take, well-tolerated daily capsule
How to use
*For a 6-month plan paid upfront. Actual price depends on the product and subscription plan.
Only available by prescription from provider after virtual consultation. Actual product packaging may appear differently than shown. Compounded drugs are permitted to be prescribed under federal law but are not FDA-approved and do not undergo FDA safety, effectiveness, or manufacturing review. Individual results may vary.

A simple pill with big potential
Metformin has been around for decades, but researchers are now exploring it for something bigger: healthy aging. By supporting how your body handles energy, stress, and inflammation, it could help keep you feeling better, longer.
Aging, rewritten
Supports cellular health
Metformin activates AMPK, which promotes mitochondrial biogenesis, improves mitochondrial function, and enhances autophagy, or the process your body uses to clear out damaged cells.¹ This leads to more efficient energy production and better overall cellular health, both key factors for mental performance and healthy aging.
Reduces inflammation
Metformin has been shown to suppress inflammatory pathways and reduce production of inflammatory cytokines. It also decreases reactive oxygen species (ROS), which can damage DNA and accelerate aging.¹ Together, these effects help protect tissues from chronic, low-grade inflammation and oxidative damage.
Improves metabolic function
Metformin improves insulin sensitivity, reduces glucose production in the liver, and can help decrease appetite, making it a powerful tool for managing weight and maintaining metabolic balance.² These effects may also reduce the risk of developing metabolic syndrome and type 2 diabetes as we age.
Promotes healthy aging
Metformin may lengthen both lifespan and healthspan by targeting core aging mechanisms like inflammation, mitochondrial dysfunction, and cellular senescence. This has also been shown to delay the onset of age-related diseases including some cancers, cardiovascular disease, and neurodegeneration.¹
What is Metformin ER?
Metformin is a time-tested prescription medication originally developed to help manage blood sugar levels in people with type 2 diabetes. In recent years, it’s gained attention far beyond that, being explored for its potential to support healthy aging, metabolic function, and cellular resilience. Formulated as an extended-release (ER) capsule, our Metformin ER is designed for easy absorption and reduced side effects. Whether you’re focused on energy, inflammation, or long-term health span, Metformin may be a powerful addition to your proactive wellness routine.

Taking Metformin
Metformin’s main role is to improve how the body responds to insulin, but its impact goes deeper. It activates AMPK, an enzyme that signals cells to enter repair mode—potentially reducing oxidative stress, lowering inflammation, and optimizing how your body uses energy. This kind of cellular upkeep may help slow age-related decline and support long-term health. On top of all this, our extended release (ER) formula acts to lessen the stress on your digestive system, making for a more comfortable treatment.
What to expect
Our Metformin ER is designed to work behind the scenes to support long-term metabolic maintenance with minimal side effects. While there won’t be an overnight change, many people report steadier energy, easier weight management, and improved biomarkers tied to longevity. Over time, you’ll start to notice more of the potential anti-aging benefits.

Side effects
Like all treatments, Metformin can come with a few side effects. The good news? Our extended-release formula along with starting with lower dosing helps mediate these side effects, and symptoms are usually short-lived.
Digestive upset
Things like nausea, bloating, or diarrhea are common, especially in the first week or two. Eating small, frequent meals with adequate hydration can help.
Vitamin B12 deficiency
B12 levels may decline a bit in some people. It’s worth checking levels annually and supplementing if needed. Signs of low B12 like fatigue or tingling are rare and reversible.
Reduced appetite
While it can be helpful for weight loss, it’s important to flag any large changes in appetite with your provider so that your dosage or treatment plan can be adjusted accordingly.
How to get Metformin ER
Intake forms
10-15 minutes
Answer a few quick questions about your health history and goals.
Doctor review
Up to 2 days
A licensed provider will determine if the treatment is the right fit for you.
Order processing
5-7 business days
Your order will be compounded and processed, if prescribed.
Free 2-day shipping
2 days
Your treatment will ship quickly and discreetly to your door at no cost.
Common questions about Metformin
Who is a good candidate for Metformin ER?
Could Metformin cause my blood sugar to drop?
Do I need to worry about lactic acidosis while I am taking Metformin?
Will Metformin help me lose weight?
Can Metformin be taken long-term?
How is my treatment personalized?
Need more help?
Get free personalized help from our licensed pharmacists.
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Metformin reviews
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